Home
About us
Lists
Advanced search
Data submission
Citing us
Help
Contact
Nephrocalcin (Osteocalcin)
Modulator score = 420
(score < 50 : weak,
score ≥ 50 : solid )
General Information
Protein
Common name
Nephrocalcin (Osteocalcin)
Alternative name
Bone Gla protein (BGP), Gamma-carboxyglutamic acid-containing protein
UniProt ID
P02818
Isoform
P02818
Proteomic database
Protein Atlas
P02818
PeptideAtlas
P02818
Gene
Gene name
bone gamma-carboxyglutamate protein
Gene symbol
BGLAP
Genome annotation database
Ensembl
ENSG00000242252
Modulatory effects
Crystallization
Inhibitor
number of references
1
Evidence that nephrocalcin and urine inhibit nucleation of calcium oxalate monohydrate crystals. (1991)
Crystal growth
Inhibitor
number of references
5
Characterization of Ca(2+)-binding sites in the kidney stone inhibitor glycoprotein nephrocalcin using vanadyl ions: different metal binding properties in strong and weak inhibitor proteins revealed by EPR and ENDOR. (1996)
Characterization of calcium-binding sites in the kidney stone inhibitor glycoprotein nephrocalcin with vanadyl ions: electron paramagnetic resonance and electron nuclear double resonance spectroscopy. (1994)
The effect of warfarin on urine calcium oxalate crystal growth inhibition and urinary excretion of calcium and nephrocalcin. (1993)
Inhibitors within the nephron. (1991)
Crystal adsorption and growth slowing by nephrocalcin, albumin, and Tamm-Horsfall protein. (1988)
Crystal aggregation
Inhibitor
number of references
2
Inhibitors within the nephron. (1991)
Inhibition of calcium oxalate monohydrate crystal aggregation by urine proteins. (1989)
Crystal-cell adhesion
Inhibitor
number of references
1
Adhesion of calcium oxalate monohydrate crystals to renal epithelial cells is inhibited by specific anions (1995)