Fibronectin
Modulator score = 360
(score < 50 : weak, score ≥ 50 : solid )

Experimental evidence∑experimental score = 350

Modulator functions

number of references  7

Crystal crystallization

PMID/DOI Title name Year
PMID:30701361 Modulatory effects of fibronectin on calcium oxalate crystallization, growth, aggregation, adhesion on renal tubular cells, and invasion through extracellular matrix. 2019

Crystal growth

PMID/DOI Title name Year
PMID:30701361 Modulatory effects of fibronectin on calcium oxalate crystallization, growth, aggregation, adhesion on renal tubular cells, and invasion through extracellular matrix. 2019
PMID:12706004 The role of osteopontin on calcium oxalate crystal formation. 2003
PMID:11025758 Fibronectin as a potent inhibitor of calcium oxalate urolithiasis. 2000

Crystal aggregation

PMID/DOI Title name Year
PMID:30701361 Modulatory effects of fibronectin on calcium oxalate crystallization, growth, aggregation, adhesion on renal tubular cells, and invasion through extracellular matrix. 2019
PMID:12706004 The role of osteopontin on calcium oxalate crystal formation. 2003
PMID:11025758 Fibronectin as a potent inhibitor of calcium oxalate urolithiasis. 2000

Crystal-cell adhesion

PMID/DOI Title name Year
PMID:30701361 Modulatory effects of fibronectin on calcium oxalate crystallization, growth, aggregation, adhesion on renal tubular cells, and invasion through extracellular matrix. 2019
PMID:13680020 Renal tubular cell injury and fibronectin. 2003
PMID:11549512 Strong inhibition of crystal-cell attachment by pediatric urinary macromolecules: a close relationship with high urinary citrate secretion. 2001
PMID:11025758 Fibronectin as a potent inhibitor of calcium oxalate urolithiasis. 2000
PMID:8498532 Regulation of renal epithelial cell endocytosis of calcium oxalate monohydrate crystals. 1993
Predicted evidence∑predicted score = 10

Calcium-binding
Oxalate-binding