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NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3)
Modulator score = 105
(score < 50 : weak,
score ≥ 50 : solid )
General Information
Protein
Common name
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3)
Alternative name
Regulatory protein SIR2 homolog 3, SIR2-like protein 3
UniProt ID
Q9NTG7
Isoform
Q9NTG7
Proteomic database
Protein Atlas
Q9NTG7
PeptideAtlas
Q9NTG7
Gene
Gene name
sirtuin 3
Gene symbol
SIRT3
Genome annotation database
Ensembl
ENSG00000142082
Modulatory effects
Crystallization
No solid experimental evidence
Crystal growth
No solid experimental evidence
Crystal aggregation
No solid experimental evidence
Crystal-cell adhesion
Inhibitor
number of references
2
Sirtuin 3 suppresses the formation of renal calcium oxalate crystals through promoting M2 polarization of macrophages. (2019)
SIRT3 inhibited the formation of calcium oxalate-induced kidney stones through regulating NRF2/HO-1 signaling pathway. (2018)